Anna G. Wenzel,
Professor of Chemistry; Natural Sciences Convener, Chemistry
Phone: 70912
Academic History
- (2003-2006) NIH Postdoctoral Scholar; Caltech, Pasadena, CA
- (1998-2003) Ph.D., M.A.; Harvard University, Cambridge, MA
- (1994-1998) B.S.; University of California, San Diego, La Jolla, CA
Interests
Asymmetric Catalysis, Organometallic Chemistry, and Organic Synthesis
Courses Taught
- Chemistry 116, 116L (Fall)
Selected Research and Publications
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PEER-REVIEWED ARTICLES
- King, B. H.; Wang, M. L.; Jesse, K. A.; Kaur, G.; Tran, B.; Walser-Kuntz, R.; Iafe, R. G.; Wenzel, A. G.* “Silver-Catalyzed, N-Formylation of Amines Using Glycol Ethers.” J. Org. Chem.2020, 85, 13256-13263.
- Wenzel, A. G.;* Casper, S.; Galvin, C. J.; Beck, G. E. “Science and Business of Medicinal Chemistry: a “Bench-to-Bedside” Course for Non-Majors.” J. Chem. Ed. 2020, 97, 414-420.
- Oakley, J. V.; Stanley, T. J.; Jesse, K. A.; Cain, S. E.; Wenzel, A. G.;* Iafe, R. G.* “Gold-Catalyzed Friedel–Crafts-like Reaction of Benzylic Alcohols to Afford 1,1-Diarylmethanes.” Eur. J. Org. Chem. 2019, 42, 7063-7066.
- Vinson, A. R. S.; Davis, V. K.; Arunasalam, A.; Jesse, K. A.; Hamilton, R. E.; Shattuck, M. A.; Hu, A. C.; Iafe, R. G.; Wenzel, A. G.* “Gold-Catalyzed, SN1-Type Reaction of Alcohols to Ethers and Cbz-Protected Amines.” Synlett 2015, 26, 765-770.
- Grant-Overton, S.; Buss, J. A.; Smith, E. H.; Gutierrez, E. G.; Moorhead, E. J.; Lin, V. S. Wenzel, A. G.* “Efficient Microwave Method for the Oxidative Coupling of Phenols.” Synth. Commun. 2015, 45, 331-337.
- Lipshutz, B. H.*; Bošković, Z.; Crowe, C. S.; Davis, V. K.; Whittemore, H. C.; Vosburg, D. A.*; Wenzel, A. G.* “Green “Click” and Olefin Metathesis Chemistry in Water at Room Temperature Enabled by Biodegradable Micelles.” J. Chem. Ed. 2013, 90, 1514-1517.
- Wagner, A. M.; Knezevic, C. E.; Wall, J. L.; Sun, V. L.; Buss, J. A.; Allen, L. T.; Wenzel, A. G.* “A Copper(II)-catalyzed Sequential Michael-Aldol Reaction for the Preparation of 1,2-Dihydroquinoline Carboxylic Acid Derivatives.” Tetrahedron Lett. 2012, 53, 833-836.
- Wenzel, A. G.*; Blake, G.; Vander Velde, D. G.; Grubbs, R. H. “Characterization and Dynamics of Substituted Ruthenacyclobutanes Relevant to the Olefin Cross-Metathesis Reaction.” J. Am. Chem. Soc. 2011, 133, 6429-6439.
- Gutierrez, E. G.; Moorhead, E. J.; Smith, E. H.; Lin, V.; Ackerman, L. K. G.; Sun, V.; Grant, S.; Wenzel, A. G.* “Electron-Withdrawing Biphenyl-diol Compounds for Asymmetric Catalysis.” Eur. J. Org. Chem. 2010, 3027-3031.
- Moorhead, E. J.; Wenzel, A. G.* “Two Undergraduate Experiments in Organic Polymers: the Preparation of Polyacetylene and Telechelic Polyacetylene via Ring-Opening Metathesis Polymerization.” J. Chem. Ed. 2009, 86, 973-975.
- O’Connor, J. M.; Wenzel, A. G.; Hiibner, K. “Iridium(III)-Vinylidene Chemistry: Conversion of an Iridacyclopentadiene-Chlorido Complex and Terminal Alkynes to Iridacyclopentadiene-Vinyl Complexes.” Inorganica Chimica Acta 2008, 361, 3033-3041.
- Hong, S. H.; Wenzel, A. G.; Salguero, T. T.; Day, M. W.; Grubbs, R. H. “Decomposition of Ruthenium Olefin Metathesis Catalysts.” J. Am. Chem. Soc. 2007, 129, 7961-7968.
- Wenzel, A. G.; Grubbs, R. H. “Ruthenium Metallacycles Derived from 14-Electron Complexes. New Insights into Olefin Metathesis Intermediates.” J. Am. Chem. Soc. 2006, 128, 16048-16049.
- Ritter, T.; Hejl, A.; Wenzel, A. G.; Funk, T.; Grubbs, R. H. “Catalyst Comparison in Olefin Metathesis Reactions and Generalized Reaction Procedures.” Organometallics, 2006, 25, 5740-5745.
- Wenzel, A.; Lalonde, M. P.; Jacobsen, E. N. “Divergent Stereoinduction Mechanisms in Urea-Catalyzed Additions to Imines.” Synlett 2003, 1919-1922.
- Wenzel, A. G.; Jacobsen, E. N. “Asymmetric Catalytic Mannich Reactions Catalyzed by Urea Derivatives: Enantioselective Synthesis of B-Aryl-B-Amino Acids.” J. Am. Chem. Soc. 2002, 124, 12964-12965.
- O’Connor, J. M.; Chen, M.–C.; Fong, B. S.; Wenzel, A. G.; Gantzel, P. “Conversion of a Metallacyclobutene to Cobalt-Allene Complexes.” J. Am. Chem. Soc. 1998, 120, 1100-1101. BOOKS
- Handbook of Metathesis, 2nd Ed.; Grubbs, R. H.; Wenzel, A. G., Eds.; Wiley-VCH: New York, Vol. 1, 2015.
- Wenzel, A. G.; Chatterjee, A. K.; Grubbs, R. H. “Olefin Cross-Metathesis.” In Comprehensive Organometallic Chemistry III: Review of the Literature 1993-2005; Ojima, I.; Hiyama, T., Eds.; Elsevier Ltd: Oxford; Vol. 11, 2006.
- Wenzel, A. G.; Jacobsen, E. N. “Asymmetric Catalysis in the Enantioselective Synthesis of B-Amino Acids.” In Enantioselective Synthesis of B-Amino Acids, 2nd Ed.; Juaristi, E.; Soloshonok, V. A., Eds.; WILEY-VCH: New York, 2005. ESSAYS AND EDITORIALS
- Wenzel, A. G. “The Chemical Analysis of Scripps’ 2013 Olive Oil.” (Published online 7/4/2014) http://magazine.scrippscollege.edu/wp-content/uploads/files/2014-summer.pdf
- Wenzel, A. G. “Olefin Metathesis and its Application.” Molecules –Advance Editorial for Special Issue (Published online 11/10/2010) http://www.mdpi.com/journal/molecules/special_issues/olefin_metathesis/
- Wenzel, A. G. “The Scanning of Saint Michael.” (Published online 4/26/2010) http://media.scrippscollege.edu/feature-stories/the-scanning-of-st-michael